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Levamisole Hydrochloride
Levamisole Hydrochloride is the levo-isomer of tetramisole, a broad-spectrum anthelmintic drug with strong efficacy against roundworms, hookworms, pinworms, and strongyloidiasis. It also functions as an immunomodulator for treating rheumatic diseases. When parasites develop resistance to benzimidazole anthelmintics, Levamisole Hydrochloride can be alternatively used as a cross-treatment option.
- Overview
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| Chemical Name | (S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride | ||
| Cas No. | 16595-80-5 | Molecular Formula | C₁₁H₁₂N₂S·HCl |
| Quality level | USP/EP/CP | Molecular Weight | 240.75 g/mol |
| Appearance | White to off-white crystalline powder, odorless with a bitter taste. | ||
| Structural formula |  |
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Key Features of Levamisole Hydrochloride:
● Broad-Spectrum Anthelmintic Activity:
● Targets intestinal parasites (roundworms, hookworms, pinworms) with high single-dose efficacy.
● Effective in livestock (pigs, cattle, poultry) and aquaculture (fish parasites).
● Immune Modulation:
● Boosts cellular immunity, ideal for immunocompromised animals.
● Rapid Action & reliability:
● Peak plasma concentration in 2-4 hours; 90% parasite expulsion in 24 hours.
● Safe for pregnant animals at recommended doses.
● International Quality Standards:
● Complies with USP/EP/BP/CP pharmacopeia requirements.
Technical Parameters:
| Test Item | Specification |
| Assay (HPLC) | 98.5%~101.0% |
| Optical Rotation ([α]D²⁵) | -104° to -108° (aqueous solution) |
| Loss on Drying | ≤0.5% |
| Microbial Limits | Complies with EP 2.6.12 |
| Residual Solvent (Ethanol) | ≤5000 ppm (ICH Q3C) |
Applications:
● Dosage & Formulations:
| Animal type | Formulation | Dosage (mg/kg BW) |
| Cattle/Sheep | Tablets/Injection | 7.5-10 |
| Swine | Premix/Water additive | 5-8 |
| Poultry | Soluble powder | 10-15 |
● Typical Customer Cases:
● Veterinary Pharmaceutical Companies: Used to produce anthelmintic premixes and injections, exported to markets like: Southeast Asian and African markets.
● Aquaculture: Applied for parasite control in fish, improving breeding survival rates.
● Pharmaceutical Companies: Used as raw material to produce tablets and liniments for cancer adjuvant therapy and immune modulation.
Supply Chain:
● Packaging: 25kg sealed drums (double polyethylene-lined), customizable (1kg/bag).
● Storage: Protect from light, sealed, temperature ≤30°C, humidity≤65%.
● Transport: Class 6.1 hazardous.
Why Choose Us?
● Assured stable supply: Our factory: Jiangsu Quality Horizons Pharmtech (abbreviated as “QH Pharm”) has the annual capacity of 1000mt, supports bulk orders with guaranteed supply.
● Global high Quality Standards: Complies with highest level of USP/EP/CP pharmacopeia requirements.
● Full Supply Chain Control: Cost-effective, quality stable and traceable production from raw materials to formulations.
● Technical supports: Parasite resistance testing supports, Assist in designing combination formulations.
● Customization: Stability optimization.
● Global Compliance: GMP & CEP Certified, EDMF/ASMF/DMF support.
Our Levamisole Hydrochloride quality complies with USP/EP/BP/CP pharmacopoeia.
Under the professional manufacturing specifications and strict quality systems, we can assure you that our factory’s Levamisole Hydrochloride will be of the highest quality and consistency level from batch to batch and the most reliable source to be used in your manufacturing and R&D application.
Safety & Compliance
● Handling: Wear protective gear to avoid skin/eye contact.
● Documents: CoA, MSDS, GMP certificates; third-party lab testing available.
Request Samples & Quotes：
📧 Email:[email protected]
🌐 Website:www.gtgmt.com
📱 WhatsApp:+86-13601562190
